TY - JOUR AU - Dudley, Jeffrey N. AU - Hong, Celine S. AU - Hawari, Marwan A. AU - Shwetar, Jasmine AU - Sapp, Julie C. AU - Lack, Justin AU - Shiferaw, Henoke AU - Johnston, Jennifer J. AU - Biesecker, Leslie G. AU - NISC Comparative Sequencing Program PY - 2021 DA - 2021/04/08 TI - Low-level variant calling for non-matched samples using a position-based and nucleotide-specific approach JO - BMC Bioinformatics SP - 181 VL - 22 IS - 1 AB - The widespread use of next-generation sequencing has identified an important role for somatic mosaicism in many diseases. However, detecting low-level mosaic variants from next-generation sequencing data remains challenging. SN - 1471-2105 UR - https://doi.org/10.1186/s12859-021-04090-y DO - 10.1186/s12859-021-04090-y ID - Dudley2021 ER -