Table 1 Summary of comparison of EzMAP with some of the pre-existing microbiome analysis tools (standalone programs only)
Features | EzMAP | QIIME studio | GenePiper | BiomMiner | iMAP |
|---|---|---|---|---|---|
Installation | |||||
 Command-line interface | Partial | Yes | No | Yes | Yes |
Graphical user interface | |||||
 Upstream analysis | Yes | Yes | Not applicable | No | No |
 Downstream analysis | Yes | Yes | Yes | Yes | Yes |
Upstream analysis | |||||
 Sequence pre-processing | Yes | Yes | No | Yes | Yes |
 OUT cluster and taxonomy assignments | Yes | Yes | No | Yes | Yes |
 Data Summary | Yes | Yes | No | Yes | Yes |
 Analysis run time (Approx. Hrs) | 8:24 | 8:20 | – | 7:50 | 8:18 |
Downstream analysis | |||||
 Alpha diversity | Yes | Yes | Yes | Yes | Yes |
 Beta diversity: Ordination plots | Yes | Yes | Yes | Yes | Yes |
 Basic statistics | Yes | Yes | Yes | Yes | Yes |
 Differential abundance analysis | |||||
  LefSe | Yes | No | No | No | No |
  DESeq2 | Yes | No | No | Yes | No |
 Functional analysis | |||||
  PICRUSt | Yes | No | No | No | No |
  Tax4Fun | Yes | No | No | No | No |
  FunGuild | Yes | No | No | No | No |