Fig. 3

Simulation results. Each panel in the above figure shows a bar plot of the power of the seven methods in one simulation setting. The 48 settings evaluate three different enpoints as indicated by the column headers with simple or complex associations in 100 or 1000 genes (in blocks of rows with gray or azure backgrounds) as indicated by the labels on the left for sample size \(n=10\), \(n=20\), \(n=50\), or \(n=100\) as indicated by the labels on the right. Each bar represents the power of one method; the colors for the methods are indicated by the legend at the bottom. A filled bar indicates that the empirical level was less than 6% and a hollow bar indicates that the empirical level was greater than 6%. All methods were performed with a nominal level of 5%. In each panel, a gold border around a bar indicates that the method had the best power or was within 1% of the best power and kept its empirical level less than 6%. Each panel includes dashed horizontal lines at 50% and 100% power