Table 1 Properties of some gene-set testing methods
From: Gene-set distance analysis (GSDA): a powerful tool for gene-set association analysis
Property | GSDA | GS(E)A+SAFE | GT+TOTS+POST | MRPP |
|---|---|---|---|---|
Linear | \(\checkmark\) | \(\checkmark\) | \(\checkmark\) | \(\checkmark\) |
Non-linear | \(\checkmark\) | Â | Â | \(\checkmark\) |
Non-monotone | \(\checkmark\) | Â | Â | \(\checkmark\) |
Categorical | \(\checkmark\) | \(\checkmark\) | \(\checkmark\) | \(\checkmark\) |
Quantitative | \(\checkmark\) | \(\checkmark\) | \(\checkmark\) | Â |
Event-time | \(\checkmark\) | \(\checkmark\) | \(\checkmark\) | Â |
Self-contained | \(\checkmark\) | Â | \(\checkmark\) | \(\checkmark\) |
Competitive | Â | \(\checkmark\) | Â | Â |
Model-fitting | Â | \(\checkmark\) | \(\checkmark\) | Â |
Resampling | \(\checkmark\) | \(\checkmark\) | \(\checkmark\) | \(\checkmark\) |