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Table 1 Properties of some gene-set testing methods

From: Gene-set distance analysis (GSDA): a powerful tool for gene-set association analysis

Property GSDA GS(E)A+SAFE GT+TOTS+POST MRPP
Linear \(\checkmark\) \(\checkmark\) \(\checkmark\) \(\checkmark\)
Non-linear \(\checkmark\)    \(\checkmark\)
Non-monotone \(\checkmark\)    \(\checkmark\)
Categorical \(\checkmark\) \(\checkmark\) \(\checkmark\) \(\checkmark\)
Quantitative \(\checkmark\) \(\checkmark\) \(\checkmark\)  
Event-time \(\checkmark\) \(\checkmark\) \(\checkmark\)  
Self-contained \(\checkmark\)   \(\checkmark\) \(\checkmark\)
Competitive   \(\checkmark\)   
Model-fitting   \(\checkmark\) \(\checkmark\)  
Resampling \(\checkmark\) \(\checkmark\) \(\checkmark\) \(\checkmark\)
  1. GS(E)A refers to GSEA and GSA