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Table 4 Comparison of specificity, sensitivity and F1 scores of transcripts assemblies generated by Strawberry, Scallop, Stringtie, PsiCLASS and FINDER for three model organisms—A. thaliana, O. sativa and Z. mays

From: FINDER: an automated software package to annotate eukaryotic genes from RNA-Seq data and associated protein sequences

 

Arabidopsis thaliana

Oryza sativa

Zea mays (RefSeq)

STRAWBERRY

SCALLOP

STRINGTIE

PSICLASS

FINDER

STRAWBERRY

SCALLOP

STRINGTIE

PSICLASS

FINDER

STRAWBERRY

SCALLOP

STRINGTIE

PSICLASS

FINDER

Base specificity

38.41

37.34

58.35

62.63

74.46

22.6

24.23

39.83

36.64

42.46

30.06

29.6

49.33

55.61

62.97

Base sensitivity

87.06

85.3

80.22

70.83

71.45

78.2

77.64

70.87

60.27

61.43

81.2

79.08

76.98

70.52

72.1

Base F1 score

53.3

51.94

67.56

66.48

72.92

35.07

36.93

51

45.57

50.21

43.88

43.08

60.13

62.18

67.23

Exon specificity

43.86

70.64

74.82

89.82

91.79

23.51

42.97

51.7

66.29

67.67

37.18

52.37

60.33

77.76

79.71

Exon sensitivity

85.3

79.67

79.29

69.54

69.93

79.08

76.65

75.47

65.75

64.81

85.03

81.68

81.77

75.88

74.38

Exon F1 score

57.93

74.88

76.99

78.39

79.38

36.24

55.07

61.36

66.02

66.21

51.74

63.82

69.43

76.81

76.95

Intron specificity

55.32

78.7

80.58

95.29

96.55

29.13

48.56

56.5

71.41

73.24

43.79

56.74

64.79

82.8

84.86

Intron sensitivity

92.06

89.99

87.75

77.63

76.51

85.84

85.41

83.28

71.72

71.03

90.19

86.69

86.05

78.99

78.12

Intron F1 score

69.11

83.97

84.01

85.56

85.37

43.5

61.92

67.32

71.56

72.12

58.96

68.59

73.92

80.85

81.35

Transcript specificity

6.88

24.84

35.02

56.82

60.04

1.59

9.03

14.26

24.22

24.54

6.96

17.8

26.23

43.96

44.78

Transcript sensitivity

31.68

32.19

35.23

31.8

37.21

26.69

29.43

31.2

32.37

33

48.71

46.71

47.76

42.48

42.25

Transcript F1 score

11.3

28.04

35.12

40.78

45.95

3

13.82

19.57

27.71

28.15

12.18

25.78

33.86

43.21

43.48

Gene specificity

33.16

36.51

63.7

65.67

67.33

17.61

20.16

35.69

40.39

32.79

21.83

26.33

47.43

54.04

52.3

Gene sensitivity

44.77

46.18

50.59

49.33

57.96

28.91

31.79

33.65

34.54

35.05

55.2

55.85

58.03

57.22

57.35

Gene F1 score

38.1

40.78

56.39

56.34

62.29

21.89

24.67

34.64

37.24

33.88

31.29

35.79

52.2

55.58

54.71

  1. Best performance is indicated by bold values