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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Paired-end small RNA sequencing reveals a possible overestimation in the isomiR sequence repertoire previously reported from conventional single read data analysis

Fig. 3

GSEA enrichment plots. Pre-ranked GSEA analysis was performed using as metric the normalized log2FoldChange estimate from DESEq2 between SR and PE datasets from the same samples (30 normal serum samples, filtering for miRNA and isomiR sequences present in at least 10 samples). Enrichment of each class of isomiR was assessed. Only iso_snv class isomiRs showed significant enrichment. a iso_snv, b iso_5p, c iso_3p, d iso_add3 e canonical enrichment plots. Please see Table 1 for complete output results

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BMC Bioinformatics

ISSN: 1471-2105

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