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Fig. 2 | BMC Bioinformatics

Fig. 2

From: scSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy

Fig. 2

Reliability evaluation of sensitive gene identification in PbmcBench PBMC data set. a There were 211, 274, 274 and 314 sensitive genes in each sample of the PbmcBench PBMC data set, with 96 sensitive genes in common; b The KEGG enrichment result of these 96 common sensitive genes showed that these sensitive genes were obviously enriched in pathways related to cellular stress response; c In the first sample of PbmcBench PBMC1, we compared three types of genes (cell marker genes, HK genes, and sensitive genes) by their entropy and CV-rank in total cells (dotted line represent the threshold of HVGs); d We compared these three types of genes by their entropy and number of clusters with high CV-rank (top 2000); e, f We used the Kruskal–Wallis test to compare these three types of genes from the aspects of entropy and number of clusters with high CV-rank (top 2000)

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BMC Bioinformatics

ISSN: 1471-2105

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