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Fig. 11 | BMC Bioinformatics

Fig. 11

From: Genome-wide variant-based study of genetic effects with the largest neuroanatomic coverage

Fig. 11

The workflow of the genetic algorithms. Coding = the SNP sets code into a 3-bit code; Initialization = the generation of initial data set; Tournament Strategy = mining the best code from a set of codes; Intersection = exchanging parents’ code in a random site; Mutation = generating a new 3-bit code; Offspring = the result of Intersection or Mutation; Fitness function = based on the p value of 3 SNPs affecting 116 ROIs or a specific ROI, the SNPs sets with minimal p value are picked out as the parent; Decoding = the 3-bit code decode into corresponding SNP sets

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