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Table 1 Mismatch and phase-switch error rates of different sequencing technologies and haplotype assembly methods

From: DR2S: an integrated algorithm providing reference-grade haplotype sequences from heterozygous samples

Error class

Technology

Method

Mean error rate

Reduction DR2S (%)

Mismatch

ONT

DR2S

0.00398

0

HapCUT2

0.01033

61.47

WhatsHap

0.00921

56.79

PacBio

DR2S

0.00272

0

HapCUT2

0.00457

40.48

WhatsHap

0.00939

71.03

Switch

ONT

DR2S

0.00089

0

HapCUT2

0.00378

76.46

WhatsHap

0.00768

88.41

PacBio

DR2S

0.00000

0

HapCUT2

0.00543

100.00

WhatsHap

0.00913

100.00