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Table 1 Design targets for novel antimicrobial peptides for ease of FMOC synthesis

From: Combining genetic algorithm with machine learning strategies for designing potent antimicrobial peptides

Property

Target

Amino acid length

7 to 15

AGGRESCAN score

− 1.25

Cysteine count

0

Net positive charge

 + 1 to + 5

Matching CLN-MLEM2 rule count

8–12