Table 2 Screened antimicrobial activities against S. epidermidis by the candidate antimicrobial peptides by the MLEM2 rule categories (AMP-1, AMP-2, AMP-3) and positive AMP control, Hp1404. Underlined letters indicate residues conserved in novel peptides compared to Hp1404
Agent | Sequence | Concentration (mg/mL) | Inhibition zone (cm) |
|---|---|---|---|
Ampicillin | n/a | 0.01 | 1.6 |
Hp1404 (crude) | GILGKLWEGVKSIF | 4.00 | 2.3 |
AMP-1 (crude) | ATLGVLWESIRGHR | 4.00 | 0 |
AMP-2 (crude) | ATLGVLWEGARGHT | 4.00 | 1.2 |
AMP-3 (crude) | GTLANGWEGVRTNH | 4.00 | 0 |