From: A detailed map of coupled circadian clock and cell cycle with qualitative dynamics validation
Cell cycle phase | Circadian clock entity | Mutation |
---|---|---|
early G1 | HSP90 | LoF |
late G1 | HSP90 | LoF |
early S | none identified | |
late S | HSP90 | LoF |
G2 | PER:CRY:CSNK1:CLOCK:ARNTL | GoF |
MYC:MIZ1 | GoF | |
WEE1 | LoF | |
ARNTL | LoF | |
CLOCK | LoF | |
CSNK2A | LoF | |
MIZ1 | LoF | |
NAD+ | LoF | |
PARP1 | LoF | |
NR1D1 | GoF | |
NMN* | LoF | |
NMNAT* | LoF | |
M | all controls of G2 and | |
CCNB1:CDK1 | LoF |