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Table 9 Feature categories that are used to represent miRNA–target interactions

From: Comprehensive machine-learning-based analysis of microRNA–target interactions reveals variable transferability of interaction rules across species

Category

No. of features

Description

Group

Seed features

13

Seed composition and properties

High-level

Free energy

7

Free energy of the duplex and the mRNA at different regions

High-level

mRNA composition

62

mRNA composition in the site and flanking regions

High-level

miRNA pairing

38

Binding information at each miRNA position and across the miRNA–target duplex

Low-level

Site accessibility

370

Unpaired probabilities of each base

Low-level

Total

490