Fig. 1

Schematic representation of chromosome 1 region analyzed. The ACKR1 gene is bordered by the 2 genes CADM3 in centromeric and FCER1A in telomeric direction at chromosomal position 1q23.2 (a). The structure of the ACKR1 gene (b) comprises 2 exons (closed boxes) and include the coding sequence (CDS, black) and the 5’- and 3’-untranslated region (UTR, grey). The intron 1 joins the 2 exons (black line). The number of SNVs observed in the for the dbSNP (b) and 1000GP databases (c) are shown for the 5’-UTR, CDS, intron, CDS and 3’-UTR