Fig. 1

Global distribution and gene-wise mutation analysis of the SARS-CoV-2 genome mutations. a Genomic hotspot mutations (recurrence > 40,000 samples) distribution across the genome. Mutations have been labelled with protein change in the plot. The intergenic and synonymous mutations are colored grey. The gene annotation track on the x-axis is not to scale. b Proportion of synonymous and nonsynonymous mutations across all the SARS-CoV-2 genes, c proportion of mutated/non-mutated bases across the SARS-CoV-2 gene features. The dotted line indicates an average fraction of mutated residues per feature (~ 0.8)