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Table 5 Human and bovine MHCI epitopes with presentation by an exceptional range of host alleles

From: Proteome-wide analysis of Coxiella burnetii for conserved T-cell epitopes with presentation across multiple host species

Pos

GenBank ID

Peptide

NB

WB

SB

Gene Name

Locus Tag

Species

Location

213*

AAO89864.1

FVAPVTHLF

74

25

49

 

CBU_0307

Human

SECRETED

54

AAO91456.1

HTFPGVIQL

76

30

46

 

CBU_1967

Human

MEMBRANE(non-PSE)

113*

AAO91555.1

ATYGHIHQM

75

33

42

 

CBU_2071

Human

MEMBRANE(non-PSE)

33

AAO89719.1

AQSPLLHYL

103

16

87

pilB

CBU_0155

Bovine

CYTOPLASM(non-PSE)

132

AAO89740.2

FQIKPPHQL

103

14

89

 

CBU_0180

Bovine

PSE-Cellwall

101*

AAO89868.2

YQYDNVRSV

103

24

79

 

CBU_0311

Bovine

PSE-Membrane

18

AAO89889.1

AQYPSPQLM

103

14

89

thiG

CBU_0333

Bovine

CYTOPLASM(non-PSE)

38

AAO89977.1

SQIENLHKI

103

14

89

 

CBU_0425

Bovine

CYTOPLASM(non-PSE)

220

AAO90095.2

YQKERVLTF

103

14

89

rodA

CBU_0549

Bovine

MEMBRANE(non-PSE)

10

AAO90111.1

TQFEDLPSL

103

21

82

 

CBU_0567

Bovine

CYTOPLASM(non-PSE)

258

AAO90143.1

AQKEKVFEL

103

15

88

cysQ-1

CBU_0599

Bovine

CYTOPLASM(non-PSE)

114

AAO90172.1

RAYEAIQSL

103

15

88

ppa

CBU_0628

Bovine

CYTOPLASM(non-PSE)

77

AAO90288.1

FQFTRPHYL

103

11

92

 

CBU_0748

Bovine

PSE-Lipoprotein

126

AAO90606.1

SQLPVIQKL

103

9

94

 

CBU_1093

Bovine

MEMBRANE(non-PSE)

91*

AAO90780.1

RQYERLIEV

103

20

83

 

CBU_1273

Bovine

CYTOPLASM(non-PSE)

47

AAO91182.1

AQADRIYEM

103

19

84

 

CBU_1686

Bovine

CYTOPLASM(non-PSE)

156

AAO91229.2

SQNPALHAL

103

15

88

 

CBU_1735

Bovine

PSE-Membrane

297

AAO91272.1

SQFDPRKYL

103

15

88

fbaA

CBU_1778

Bovine

CYTOPLASM(non-PSE)

  1. NetMHCpan 4.1 defined MHCI epitopes that bound 74–76 (greater than or equal to 90% total) human tested alleles or 103 (98% total) bovine tested alleles. Positions delineated with asterisks indicate that the protein associated is not found within murine data encompassing 98% of bound alleles. Total alleles bound, weak peptide interaction with alleles, and strong peptide interaction with alleles are quantified by NB, WB, and SB respectively. Protein information is outlined in columns containing the GenBank ID, gene name, and locus tag, where this information is defined through Nine Mile Phase I (RSA 493) assembly on NCBI. Pos dictates the peptide’s starting position within the protein of interest and species indicates in which species the peptide was tested for allelic interaction. Location was defined through the use of Inmembrane