Table 1 Accuracy of different methods for simulated reads with 10× coverage on chromosomes 21 and 22
From: SVNN: an efficient PacBio-specific pipeline for structural variations calling using neural networks
Method | DEL recall (%) | INS recall (%) | INV recall (%) | DUP recall (%) | TRA recall (%) | Overall recall (%) | FDR (%) |
|---|---|---|---|---|---|---|---|
Baseline method | 58.8 | 41 | 92 | 57 | 57 | 58 | 3.2 |
NGMLR-Sniffles | 61.6 | 14.5 | 92 | 60 | 66.5 | 55.5 | 2.5 |
Most sensitive method | 81.3 | 46.2 | 95 | 78 | 76 | 73 | 6.8 |
SVNN | 80.8 | 46.2 | 95 | 78 | 75 | 72.2 | 5 |