Table 2 Accuracy of different methods for simulated reads with 8× coverage on chromosomes 21 and 22
From: SVNN: an efficient PacBio-specific pipeline for structural variations calling using neural networks
Method | DEL recall (%) | INS recall (%) | INV recall (%) | DUP recall (%) | TRA recall (%) | Overall recall (%) | FDR (%) |
|---|---|---|---|---|---|---|---|
Baseline method | 62.6 | 42.9 | 91 | 65 | 54.5 | 58.25 | 3.8 |
NGMLR-Sniffles | 58.4 | 13.9 | 87 | 63 | 62 | 53.1 | 3.5 |
Most sensitive method | 84.5 | 49.4 | 94 | 80 | 78 | 75.5 | 9 |
SVNN | 79.4 | 47.3 | 94 | 74 | 78 | 72.7 | 6.1 |