Skip to main content

Table 4 Comparison of 2-kupl and GATK-MuTect2 on mutations using simulated WGS data

From: 2-kupl: mapping-free variant detection from DNA-seq data of matched samples

mutations

2-kupl

GATK-MuTect2

True positive

13835

13920

False positive

1248

30

False negative

2220

2135

Recall

0.86

0.86

FDR

0.08

0.002

Precision

0.91

0.99

F1 score

0.89

0.93