Table 6 Comparison of 2-kupl, GATK-MuTect2 and Delly on structural variants using simulated WGS data
From: 2-kupl: mapping-free variant detection from DNA-seq data of matched samples
mutations | 2-kupl | GATK-MuTect2 | Delly |
|---|---|---|---|
True positive | 133 | 49 | 135 |
False positive | 27 | 0 | 16 |
False negative | 24 | 108 | 22 |
Recall | 0.85 | 0.3 | 0.86 |
FDR | 0.17 | 0 | 0.11 |
Precision | 0.83 | 1 | 0.89 |
F1 score | 0.84 | 0.47 | 0.88 |