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Table 7 Four cases of the bases between the forward reference genome and multiread when the base on the reference is C

From: An effective method to resolve ambiguous bisulfite-treated reads

Reference base

Multiread base

Phenomenon

Calculation formula

C

A

C to A

P(CA)

C

T

Unmethylated C or C to T

P(CT)+nonSNP*P(CC)

C

C

No mutation and methylated C

NonSNP*P(CC)

C

G

C to G

P(CG)

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BMC Bioinformatics

ISSN: 1471-2105

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