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Table 3 Comparative performance of Outcyte, SecretomeP and esRF

From: Prediction of unconventional protein secretion by exosomes

 

Prediction method

OutCyte

SecretomeP

esRF

SE

0.32

0.25

0.73

SP

0.72

0.65

0.78

ACC (%)

54.39

45.14

75.73

  1. SecretomeP, OutCyte and esRF models were evaluated in our independent dataset and compared with regard to sensitivity (SE), specificity (SP) and accuracy (ACC). SecretomeP predictions were obtained at http://www.cbs.dtu.dk/services/SecretomeP/ selecting the mammalian option and the default prediction threshold of 0.6. OutCyte predictions were obtained at http://www.outcyte.com selecting the “OutCyte-UPS” model and default settings