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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing

Fig. 1

Multiplexed capture (MC) decreases variance with respect to independent captures (IC), as estimated by fitting the Dirichlet distribution. Total counts/sample given on the horizontal axis; mean \(\alpha\) given on the vertical axis. \(\alpha _0\) is inversely proportional to inter-sample variance. Each line/point represents a single pool. The point indicates the median total counts across the pool, with the range given by the line. Orange indicates a multiplexed capture; blue indicates independent captures. Triangles indicate pools using Agilent (AGL) capture; squares indicate Integrated DNA Technologies (IDT)

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BMC Bioinformatics

ISSN: 1471-2105

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