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Table 4 Over- and underrepresented clinical labels within BIC consensus clusters. ER+/ER− and PR+/PR−, respectively, correspond to estrogen receptor status and progesterone receptor status, positive and negative. M, N, and T stages refer to the TNM staging system

From: Consensus clustering applied to multi-omics disease subtyping

Cluster

Over-represented labels

Under-represented labels

A

Infiltrating Ductal Carcinoma

Infiltrating Lobular Carcinoma

Her2, Luminal B

Basal, Normal-like

ER+

ER−

B

MX, N3, T3

M0

Stage III

 

Infiltrating Lobular Carcinoma

Infiltrating Ductal Carcinoma

Luminal A

Basal

ER+, PR+

ER−, PR−

C

MX, T3

M0, T2

Infiltrating Lobular Carcinoma

Infiltrating Ductal Carcinoma

Normal-like

Basal, Luminal B

ER+, PR+

ER−, PR−

D

Stage X

 

Mucinous Carcinoma

Infiltrating Lobular Carcinoma

Luminal B

Basal, Normal-like

ER+, PR+

ER−, PR−

E

T1

 

Stage I

 

Luminal A

Basal, Luminal B

ER+, PR+

ER−, PR−

F

N0

 

Stage II

Stage III

Infiltrating Ductal Carcinoma, Medullary Carcinoma, Metaplastic Carcinoma

Infiltrating Lobular Carcinoma

Basal

Luminal A, Luminal B

ER−, PR−

ER+, PR+