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Fig. 1 | BMC Bioinformatics

Fig. 1

From: MUREN: a robust and multi-reference approach of RNA-seq transcript normalization

Fig. 1

The workflow of MUREN. A The workflow takes the raw count table as input followed by log transformation; B Take all samples as targets and select a subset of samples as references, see the paragraph "Selection of multiple reference samples" for options; C Normalize each target sample with respect to each reference sample; D Integrate multiple pre-normalized counts into the final one; E Assess the goodness by examine the densities of pairwise log ratios and their skewness before and after normalization

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