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Table 12 The intersection of the first 10 pathways (sorted by the relevance of p value \(\le 0.005\)) obtained from pathDIP performing PEA using CC genes lists and the Reactome database

From: Using BioPAX-Parser (BiP) to enrich lists of genes or proteins with pathway data

Pathway Name

p value

FDRc

Bc

(1) Metabolism of proteins

3.18 × 10\(^{-74}\)

6.31 × 10\(^{-71}\)

6.31 × 10\(^{-71}\)

(2) Immune System

1.46 × 10\(^{-60}\)

9.64 × 10\(^{-58}\)

2.89 × 10\(^{-57}\)

(3) Post-translational protein modification

6.40 × 10\(^{-49}\)

3.17 × 10\(^{-46}\)

1.27 × 10\(^{-45}\)

(4) Disease

4.02 × 10\(^{-37}\)

1.33 × 10\(^{-34}\)

7.96 × 10\(^{-34}\)

(5) Gene expression (Transcription)

1.34 × 10\(^{-36}\)

3.79 × 10\(^{-34}\)

2.66 × 10\(^{-33}\)

(6) RNA Polymerase II Transcription

1.01 × 10\(^{-29}\)

2.00 × 10\(^{-27}\)

2.00 × 10\(^{-26}\)

(7) Innate Immune System

4.51 × 10\(^{-27}\)

8.13 × 10\(^{-25}\)

8.95 × 10\(^{-24}\)

(8) Cell Cycle

2.07 × 10\(^{-25}\)

2.93 × 10\(^{-23}\)

4.11 × 10\(^{-22}\)

(9) Generic Transcription Pathway

2.94 × 10\(^{-25}\)

3.88 × 10\(^{-23}\)

5.83 × 10\(^{-22}\)

(10) Transcriptional Regulation by TP53

3.27 × 10\(^{-21}\)

3.09 × 10\(^{-19}\)

6.48 × 10\(^{-18}\)

  1. In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector