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Table 14 The intersection of the first 7 pathways (sorted by the relevance of p value \(\le 0.005\)) obtained from pathDIP performing PEA using EC genes lists and the Reactome database

From: Using BioPAX-Parser (BiP) to enrich lists of genes or proteins with pathway data

Pathway Name

p value

FDRc

Bc

(1) RNA Polymerase II Transcription

5.04 × 10\(^{-11}\)

7.43 × 10\(^{-09}\)

5.94 × 10\(^{-08}\)

(2) Gene expression (Transcription)

6.83 × 10\(^{-11}\)

8.95 × 10\(^{-09}\)

8.06 × 10\(^{-08}\)

(3) Generic Transcription Pathway

1.67 × 10\(^{-10}\)

1.51 × 10\(^{-08}\)

1.97 × 10\(^{-07}\)

(4) Metabolism of proteins

6.64 × 10\(^{-07}\)

2.70 × 10\(^{-05}\)

7.83 × 10\(^{-04}\)

(5) Immune System

6.85 × 10\(^{-06}\)

2.07 × 10\(^{-04}\)

8.09 × 10\(^{-03}\)

(6) Innate Immune System

4.79 × 10\(^{-03}\)

3.25 × 10\(^{-02}\)

1.00\(\times 10^{+00}\)

(7) Translation

7.01 × 10\(^{-03}\)

4.31 × 10\(^{-02}\)

1.00\(\times 10^{+00}\)

  1. In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector