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Table 15 The first 10 enriched pathways (sorted by the relevance of p value \(\le 0.005\)) obtained from BiP performing PEA using TC genes lists and the Reactome database

From: Using BioPAX-Parser (BiP) to enrich lists of genes or proteins with pathway data

Pathway Name

p value

FDRc

Bc

(1) Mitotic Prometaphase

7.74 × 10\(^{-14}\)

2.52 × 10\(^{-11}\)

1.51 × 10\(^{-10}\)

(2) Membrane Trafficking

3.61 × 10\(^{-12}\)

8.80 × 10\(^{-10}\)

7.04 × 10\(^{-09}\)

(3) Signaling by Rho GTPases

7.67 × 10\(^{-12}\)

1.15 × 10\(^{-09}\)

1.50 × 10\(^{-08}\)

(4) Post-translational protein modification

1.49 × 10\(^{-11}\)

1.94 × 10\(^{-09}\)

2.91 × 10\(^{-08}\)

(5) Extracellular matrix organization

1.40 × 10\(^{-10}\)

1.36 × 10\(^{-08}\)

2.72 × 10\(^{-07}\)

(6) Metabolism of proteins

2.48 × 10\(^{-10}\)

2.11 × 10\(^{-08}\)

4.85 × 10\(^{-07}\)

(7) M Phase

3.18 × 10\(^{-10}\)

2.48 × 10\(^{-08}\)

6.20 × 10\(^{-07}\)

(8) Cell Cycle, Mitotic

1.17 × 10\(^{-09}\)

7.86 × 10\(^{-08}\)

2.28 × 10\(^{-06}\)

(9) Mitotic G1-G1/S phases

1.17 × 10\(^{-09}\)

7.59 × 10\(^{-08}\)

2.28 × 10\(^{-06}\)

(10) Cell Cycle

1.58 × 10\(^{-09}\)

9.64 × 10\(^{-08}\)

3.08 × 10\(^{-06}\)

  1. In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector