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Table 16 The first 10 enriched pathways (sorted by the relevance of p value \(\le 0.005\)) obtained from pathDIP performing PEA using TC genes lists and the Reactome database

From: Using BioPAX-Parser (BiP) to enrich lists of genes or proteins with pathway data

Pathway Name

p value

FDRc

Bc

(1) Immune System

1.56 × 10\(^{-28}\)

2.90 × 10\(^{-25}\)

2.90 × 10\(^{-25}\)

(2) Metabolism

9.59 × 10\(^{-28}\)

5.94 × 10\(^{-25}\)

1.78 × 10\(^{-24}\)

(3) Metabolism of proteins

6.89 × 10\(^{-27}\)

3.20 × 10\(^{-24}\)

1.28 × 10\(^{-23}\)

(4) Cell Cycle, Mitotic

5.72 × 10\(^{-26}\)

1.52 × 10\(^{-23}\)

1.06 × 10\(^{-22}\)

(5) Post-translational protein modification

3.01 × 10\(^{-24}\)

6.20 × 10\(^{-22}\)

5.58 × 10\(^{-21}\)

(6) Membrane Trafficking

1.37 × 10\(^{-21}\)

2.54 × 10\(^{-19}\)

2.54 × 10\(^{-18}\)

(7) Neutrophil degranulation

3.17 × 10\(^{-18}\)

4.91 × 10\(^{-16}\)

5.90 × 10\(^{-15}\)

(8) M Phase

5.68 × 10\(^{-16}\)

4.59 × 10\(^{-14}\)

1.06 × 10\(^{-12}\)

(9) Disease

7.65 × 10\(^{-14}\)

5.07 × 10\(^{-12}\)

1.42 × 10\(^{-10}\)

(10) Signaling by Receptor Tyrosine Kinases

4.96 × 10\(^{-13}\)

2.88 × 10\(^{-11}\)

9.21 × 10\(^{-10}\)

  1. In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector