Table 3 The intersection of the first 10 pathways obtained from CePa by performing pathway enrichment analysis by using CC genes lists and the KEGG database. The table summarises the values obtained for each topology measure employed by CePa
From: Using BioPAX-Parser (BiP) to enrich lists of genes or proteins with pathway data
Name | Weight | In degree | Out degree | Betweenness | In reachability | Out reachability |
|---|---|---|---|---|---|---|
(1) Pyrimidine biosynthesis | 0.034 | 0.031 | 0.188 | 0.031 | 0.037 | 0.037 |
(2) Inactivation of APC C via direct inhibition of the APC C complex | 0.031 | 0.047 | 0.047 | 0.037 | 0.037 | 0.037 |
(3) Removal of licensing factors from origins | 0.031 | 0.034 | 0.031 | 0.037 | 0.037 | 0.037 |
(4) CDT1 association with the CDC6 ORC origin complex | 0.031 | 0.0059 | 0.047 | 0.0058 | 0.037 | 0.037 |
(5) NCAM signaling for neurite out growth | 0.031 | 0.034 | 0.098 | 0.083 | 0.037 | 0.037 |
(6) FGFR1c and Klotho ligand binding and activation | 0.044 | 0.169 | 0.10 | 0.066 | 0.180 | 0.180 |
(7) Switching of origins to a post replicative state | 0.031 | 0.034 | 0.031 | 0.037 | 0.037 | 0.037 |
(8) Fanconi Anemia pathway | 0.031 | 0.034 | 0.031 | 0.037 | 0.037 | 0.037 |
(9) ChREBP activates metabolic gene expression | 0.044 | 0.321 | 0.400 | 0.0058 | 0.338 | 0.338 |
(10) Telomere C strand Lagging Strand Synthesis | 0.065 | 0.098 | 0.075 | 0.071 | 0.047 | 0.047 |