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Table 7 The intersection of the first 10 pathways (sorted by the relevance of p value \(\le 0.005\)) obtained from pathDIP performing PEA using EC genes lists and the KEGG database

From: Using BioPAX-Parser (BiP) to enrich lists of genes or proteins with pathway data

Pathway Name

p value

FDRc

Bc

(1) Alzheimer disease

2.47 × 10\(^{-10}\)

3.46 × 10\(^{-08}\)

6.93 × 10\(^{-08}\)

(2) Parkinson disease

7.46 × 10\(^{-09}\)

5.24 × 10\(^{-07}\)

2.10 × 10\(^{-06}\)

(3) Non-alcoholic fatty liver disease (NAFLD)

9.14 × 10\(^{-08}\)

5.13 × 10\(^{-06}\)

2.57 × 10\(^{-05}\)

(4) Cellular senescence

1.31 × 10\(^{-06}\)

4.60 × 10\(^{-05}\)

3.68 × 10\(^{-04}\)

(5) Huntington disease

4.98 × 10\(^{-06}\)

1.40 × 10\(^{-04}\)

1.40 × 10\(^{-03}\)

(6) Human T-cell leukemia virus 1 infection

8.80 × 10\(^{-06}\)

2.25 × 10\(^{-04}\)

2.47 × 10\(^{-03}\)

(7) Oxidative phosphorylation

9.73 × 10\(^{-06}\)

2.28 × 10\(^{-04}\)

2.73 × 10\(^{-03}\)

(8) Apoptosis

1.28 × 10\(^{-05}\)

2.76 × 10\(^{-04}\)

3.59 × 10\(^{-03}\)

(9) Mineral absorption

1.69 × 10\(^{-05}\)

3.17 × 10\(^{-04}\)

4.75 × 10\(^{-03}\)

(10) Cardiac muscle contraction

1.84 × 10\(^{-05}\)

3.24 × 10\(^{-04}\)

5.18 × 10\(^{-03}\)

  1. In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector