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Table 3 Number of essential proteins predicted by TGSO and 13 methods based on the Krogan database

From: An iteration model for identifying essential proteins by combining comprehensive PPI network with biological information

Methods

Top1% (37)

Top5% (184)

Top10% (367)

Top15% (551)

Top20% (734)

Top25% (918)

SC

18

96

173

256

321

380

EC

20

91

173

251

317

378

BC

20

78

145

215

273

337

DC

20

78

145

215

273

337

IC

17

83

152

226

286

337

CC

13

68

142

206

262

326

NC

23

126

208

288

344

397

PEC

24

122

201

273

324

378

CoEWC

24

124

215

291

345

401

POEM

28

131

221

298

371

428

ION

31

133

238

317

392

480

CVIM

35

141

242

327

410

479

CVIM

32

142

246

321

392

449

TGSO

35

147

262

384

447

515

  1. This table shows the commonalities and differences between TGSO and the 13 competitive methods in Table 1 based on the Krogan database