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Table 3 Number of essential proteins predicted by TGSO and 13 methods based on the Krogan database

From: An iteration model for identifying essential proteins by combining comprehensive PPI network with biological information

Methods Top1% (37) Top5% (184) Top10% (367) Top15% (551) Top20% (734) Top25% (918)
SC 18 96 173 256 321 380
EC 20 91 173 251 317 378
BC 20 78 145 215 273 337
DC 20 78 145 215 273 337
IC 17 83 152 226 286 337
CC 13 68 142 206 262 326
NC 23 126 208 288 344 397
PEC 24 122 201 273 324 378
CoEWC 24 124 215 291 345 401
POEM 28 131 221 298 371 428
ION 31 133 238 317 392 480
CVIM 35 141 242 327 410 479
CVIM 32 142 246 321 392 449
TGSO 35 147 262 384 447 515
  1. This table shows the commonalities and differences between TGSO and the 13 competitive methods in Table 1 based on the Krogan database