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Fig. 3 | BMC Bioinformatics

Fig. 3

From: CHIPIN: ChIP-seq inter-sample normalization based on signal invariance across transcriptionally constant genes

Fig. 3

Comparison of normalization efficiency for H3K27ac profiles in the shSpi1-A2B cell line within replicates (A) and across replicates (B). Average density signal is shown for 8 kb regions surrounding TSSs of “constant genes”. The first plot corresponds to the average signal before the normalization. Antibody: rabbit polyclonal against H3K27ac (ab4729, Abcam); conditions: Spi1++—Spi1 overexpressed, Spi1−—Spi1 repressed by a doxycycline-inducible shRNA

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BMC Bioinformatics

ISSN: 1471-2105

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