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Table 1 List of the 27 SNPxE interaction patterns and significance levels for the interaction of SNP5 and an environmental factor

From: SNPxE: SNP-environment interaction pattern identifier

Mode

Additive

Dominant

Recessive

Model structure1

Pattern2

SNP5-Env p-value

Pattern2

SNP5-Env p-value

Pattern2

SNP5-Env p-value

Full-int

Full_AE_oo

0.425

Full_DE_oo

0.905

Full_RE_oo

0.157

SNP + Int

Mint_SNP_AE_oo

0.930

Mint_SNP_DE_oo

0.643

Mint_SNP_RE_oo

0.539

 

Mint_SNP_AE_ro

0.186

Mint_SNP_DE_ro

0.572

Mint_SNP_RE_ro

0.121

Env + Int

Mint_Env_AE_oo

0.031

Mint_Env_DE_oo

0.310

Mint_Env_RE_oo

0.012

 

Mint_Env_AE_or

0.037

Mint_Env_DE_or

0.270

Mint_Env_RE_or

0.015

Int-only

Int_AE_oo

0.557

Int_DE_oo

0.998

Int_RE_oo

0.070

 

Int_AE_or

0.073

Int_DE_or

0.160

Int_RE_or

0.050

 

Int_AE_ro

0.026

Int_DE_ro

0.161

Int_RE_ro

0.023

 

Int_AE_rr

0.064

Int_DE_rr

0.266

Int_RE_rr

0.056

  1. 1Full-int: full interaction model with two main effects plus an interaction; SNP + int: SNP main effect plus an interaction; Env + int: environment main effect plus an interaction; and (4) Int-only: an interaction only
  2. 2_oo, _or, _ro, _rr: based on original-original, original-reverse, reverse-original and reverse-reverse coding for a SNP and an environmental factor