Fig. 3
From: Conifer: clonal tree inference for tumor heterogeneity with single-cell and bulk sequencing data
Comparison of co-clustering accuracy in B-SCITE, Conifer, and PhyloWGS models for 100 clonal trees simulated with 10 clones and 50 mutations. For \(\lambda\) = 1, 5, 10 and 1000. For single-cell data 25, 50, and 100 genotypes are extracted for each clonal tree. The number of bulk sequencing samples is 2 with a coverage of 10,000. The following errors are added to the single-cell data: the false-positive rate of 10–5, the false-negative rate of 0.2, the missing rate of 0.05, and the doublet rate of 0.1