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Table 2 Null hypothesis probabilities for differences in centrality parameters between Phase4 targets and all targets, corrected for multiple testing across both centrality metric and target classes (Benjamini–Hochberg method)

From: Centrality of drug targets in protein networks

  1. Cells are coded according to statistical significance (uncorrected α = 0.05; dark green: significant, light green: marginal significance, N.S.: not significant). Red fonts indicate lower average (t-test) or median (non-parametric) centrality observed for Phase4 targets, regardless of significance. Average probabilities are calculated over all pairwise comparisons between Phase4 and all targets (‘all’ and class specific, t test and non-parametric)