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Table 5 Null hypothesis probabilities for differences in the ‘degree-weighted’ parameter log (degree*topological coefficient) between Phase4 targets and all targets tested in networks from different database sources, corrected for multiple testing across target classes (Benjamini–Hochberg method)

From: Centrality of drug targets in protein networks

  1. Cells are color coded according to the relative difference between Phase4 and all targets. Green highlights lower values observed for Phase4 targets, indicating a dominant effect of differences in topological coefficient on the combined parameter. Blue highlights higher values observed for Phase4 targets, indicating a dominant effect of differences in degree on the combined parameter. Solid color boxes indicate statistically significant differences (uncorrected α = 0.05; dark shades: significant, light shades: marginal significance, N.S.: not significant)
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BMC Bioinformatics

ISSN: 1471-2105

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