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Fig. 4 | BMC Bioinformatics

Fig. 4

From: KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases

Fig. 4

Cluster analysis of the phylogenetic profile of human kinases. a Phylogenetic profile of human kinases. X-axis: 558 human kinase domains, ordered by the kinase group and the number of orthologs identified by KinOrtho. Y-axis: 561 clades, ordered by classification. Each dot’s color represents the coverage of the human kinase ortholog in each clade. b Phylogenetic clusters of human kinases. The human kinase domains in the x-axis are in the order of clusters and the number of orthologs. The boundaries of each cluster and classification are highlighted in red. c Top 5 understudied kinases with the most orthologs in each cluster. The number of species in each classification is shown in parentheses

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BMC Bioinformatics

ISSN: 1471-2105

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