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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA

Fig. 1

Representation of Heterocyclic Aromatic Amine Metabolism. This metabolism is divided into two steps: Phase I (in green) is known as “oxidation reaction” and catalyzed by cytochromes P450 (CYPs) and Phase II (in red) is known as a “conjugation reaction”, catalyzed by UDP-glucuronyltransferases (UGTs), N-actetyltransferases (NATs), Sulfotransferases (SULTs) or Glutathione S-transferase (GSTs)

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BMC Bioinformatics

ISSN: 1471-2105

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