Table 3 Rare driver genes in BLCA
From: Identification of driver genes based on gene mutational effects and network centrality
Rank | Gene | Mut | Mutation frequency (%) | CGC genes |
|---|---|---|---|---|
2 | SRC | 4 | 1.055409 | YES |
3 | ESR1 | 1 | 0.263852 | YES |
4 | GRB2 | 1 | 0.263852 | NO |
8 | MAPK1 | 2 | 0.527704 | YES |
9 | AR | 2 | 0.527704 | YES |
10 | PIK3R1 | 3 | 0.791557 | YES |
11 | SHC1 | 4 | 1.055409 | NO |
12 | SMAD3 | 5 | 1.319261 | YES |
13 | FYN | 3 | 0.791557 | NO |
14 | ABL1 | 7 | 1.846966 | YES |
15 | SMAD2 | 3 | 0.791557 | YES |
16 | PRKCA | 3 | 0.791557 | NO |
17 | CSNK2A1 | 5 | 1.319261 | NO |
18 | STAT3 | 6 | 1.583113 | YES |
19 | LCK | 1 | 0.263852 | YES |
20 | BRCA1 | 4 | 1.055409 | YES |
21 | AKT1 | 2 | 0.527704 | YES |
22 | PRKCD | 1 | 0.263852 | NO |