The expression landscape of JAK1 and its potential as a biomarker for prognosis and immune infiltrates in NSCLC

BMC Bioinformatics

Table 4 Correlation analysis between JAK1 and relevant genes and markers of monocytes and macrophages in GEPIA

Description	Gene markers	LUAD				LUSC
		Tumor		Normal		Tumor		Normal
		R	P	R	P	R	P	R	P
Monocyte	CD14	0.3	***	− 0.051	0.7	0.27	***	0.027	0.85
	CD115	0.51	***	0.2	0.13	0.43	***	0.32	0.024
	CD86	0.4	***	− 0.22	0.093	0.28	***	− 0.035	0.81
TAM	CCL2	0.23	***	0.16	0.24	0.23	***	− 0.02	0.89
	CD80	0.35	***	0.21	0.11	0.21	***	0.22	0.13
	CD68	0.4	***	0.01	0.94	0.28	***	0.14	0.32
M1	IRF5	0.25	***	− 0.1	0.43	0.0053	0.91	0.11	0.45
	ROS	0.2	***	0.51	***	0.31	***	0.34	0.015
	NOS2	0.0033	0.94	0.56	***	− 0.042	0.36	0.49	**
M2	CD163	0.33	***	− 0.18	0.18	0.29	***	0.074	0.61
	ARG1	0.05	0.27	0.27	0.036	− 0.027	0.55	0.14	0.34
	MS4A4A	0.33	***	− 0.29	0.024	0.22	***	− 0.038	0.79

LUAD lung adenocarcinoma, LUSC lung squamous cell carcinoma, TAM tumour-associated macrophage, M1 M1 macrophage, M2 M2 macrophage
*P < 0.01; **P < 0.001; ***P < 0.0001

ISSN: 1471-2105