Factor | Level | Value | Ref | |
---|---|---|---|---|
Genotype | Number of SNPs | 20 | SNP1, …, SNP20 | |
Number of causal SNPs | 2 | SNP1, SNP2 | ||
Minor allele frequency | 2 | 0.2, 0.4 | ||
Heritability | 7 | 0.01, 0.025, 0.05, 0.1, 0.2, 0.3, 0.4 | ||
Interaction model | 5 | M1, M2, M3, M4, M5 | [7] | |
Phenotype | Number of phenotypes | 2 | Y1, Y2 | |
Distributions | 2 | bivariate normal, bivariate gamma | ||
Correlation | 3 | 0, 0.25, 0.5 | ||
Sample | Sample size | 3 | 100, 200, 400 | |
Analysis | Methods | MR-MDR (transformed, untransformed) | [24] | |
8 | multi-CMDR | |||
multi-QMDR (FPC, WPC, WSPC) | [15] | |||
QMDR (Y1, Y2) |