Table 1 Significantly enriched GO terms and KEGG pathways of DEGs
From: Bioinformatics screening of biomarkers related to liver cancer
Category | Term | Description | Count | FDR/p value |
|---|---|---|---|---|
BP term | GO:0007268 | Chemical synaptic transmission | 44 | \(2.26e-04\) |
BP term | GO:0007062 | Sister chromatid cohesion | 24 | \(4.38e-03\) |
CC term | GO:0005576 | Extracellular region | 198 | \(2.66e-08\) |
CC term | GO:0005615 | Extracellular space | 158 | \(1.08e-04\) |
CC term | GO:0031225 | Anchored component of membrane | 26 | \(1.86e-03\) |
CC term | GO:0005886 | Plasma membrane | 386 | \(1.16e-02\) |
CC term | GO:0000775 | Chromosome, centromeric region | 16 | \(2.77e-02\) |
MF term | GO:0043565 | Sequence-specific DNA binding | 79 | \(2.65e-06\) |
MF term | GO:0005179 | Hormone activity | 24 | \(4.46e-04\) |
MF term | GO:0005509 | Calcium ion binding | 88 | \(6.24e-03\) |
MF term | GO:0008083 | Growth factor activity | 29 | \(3.83e-02\) |
KEGG pathway | hsa04080 | Neuroactive ligand–receptor interaction | 46 | \(2.33e-07\) |
KEGG pathway | hsa04110 | Cell cycle | 23 | \(8.06e-05\) |
KEGG pathway | hsa04978 | Mineral absorption | 12 | \(2.43e-04\) |
KEGG pathway | hsa05410 | Hypertrophic cardiomyopathy (HCM) | 16 | \(4.47e-04\) |
KEGG pathway | hsa04260 | Cardiac muscle contraction | 15 | \(9.36e-04\) |
KEGG pathway | hsa04261 | Adrenergic signaling in cardiomyocytes | 22 | \(1.00e-03\) |
KEGG pathway | hsa05414 | Dilated cardiomyopathy | 16 | \(1.01e-03\) |