Table 5 The output of demo system for a well-known pair of human protein and HPO term, i.e. BRCA2 and Breast cancer
Sentence | PubMed ID | Year | Curator |
|---|---|---|---|
“BRCA2, also known as FANCD1, is the most known gene that causes FA when both alleles are mutated and is associated with breast cancer risk when one allele is disrupted” | 24765528 | 2014 | Related |
“Even more prominently, inactivation of the distal FA pathway through mutations in the BRCA2 (FANCD1) gene has been reported in breast cancer [14] (familial cases [15-17]), pancreatic cancer [18, 19] and ovarian cancer [20], among others” | 26843614 | 2016 | Related |
“Our results rule out a major role of FANCI, FANCL and FANCM in familial breast cancer susceptibility, suggesting that among the 13 known FA genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer predisposition” | 19737859 | 2009 | Related |
“In addition, FANCD1 gene has been shown to be identical to BRCA2, one of the two breast cancer susceptibility genes” | 16115458 | 2005 | Related |
“Specifically, mutations in FANCD1 (BRCA2) carry an 82% lifetime risk of breast cancer, and 23% risk of ovarian cancer [24, 25]” | 28157704 | 2017 | Related |