Development of a prognostic signature of patients with esophagus adenocarcinoma by using immune-related genes

BMC Bioinformatics

Table 3 Clinical characteristics and risk scores based on Univariate and multiple Cox regression analysis

Type	B	SE	z	HR	95% CI of HR	P-value
Univariate Cox regression analysis
Age	−0.02058	0.012827	−1.60406	0.979635	0.955313–1.004576	0.108701
Sex	−0.48872	0.54149	−0.90255	0.613411	0.212243–1.772836	0.366767
T	0.200995	0.226366	0.88792	1.222619	0.784523–1.905346	0.374584
N	0.315018	0.19462	1.618634	1.370284	0.935723–2.006646	0.105526
M	0.912924	0.455467	2.004368	2.491597	1.020433–6.083766	0.045031
Stage	0.682306	0.210541	3.240722	1.978436	1.309503–2.989066	0.001192
RiskScore	0.050045	0.010946	4.572128	1.051319	1.029003–1.074116	4.83E−06
Multiple Cox regression analysis
Age	−0.02668	0.013824	−1.93036	0.973668	0.947642–1.000409	0.053563
Sex	−1.50855	0.631636	−2.38833	0.22123	0.064142–0.762945	0.016925
T	−0.43244	0.364599	−1.18606	0.648926	0.317572–1.325997	0.235598
N	−0.21311	0.287253	−0.74189	0.808066	0.460182–1.418916	0.458151
M	−2.27121	1.008249	−2.25263	0.103187	0.014302–0.744473	0.024283
Stage	1.508601	0.54772	2.754327	4.520401	1.545102–13.22504	0.005881
RiskScore	0.056974	0.012569	4.532942	1.058629	1.032862–1.085031	5.82E−06

Bold inidcates clinical features are statistically signifcant in the Univariate- or Multivariate-cox regression analysis

ISSN: 1471-2105