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Fig. 2 | BMC Bioinformatics

Fig. 2

From: GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data

Fig. 2

Screenshot of the Gene-Geneset panel in the GeneTonic application. The main navigation of the app is performed via the sidebar menu (A), while the options common to the different panels are available in the control bar (toggled with the cogs icon, close to the B circle). The main area of the Gene-Geneset panel (C) contains an interactive bipartite graph connecting genesets to their respective components, color coded according to the type and the expression changes. Upon clicking on any node, a Geneset Box (D) or a Gene Box (E) can be automatically generated for facilitating further exploration. The backbone of the graph above (F) represents a compact summary of the bipartite projections, and a table displays the most highly connected nodes (G), as potential hubs with regulatory roles in multiple genesets

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