Table 3 AUC results for interaction prediction under validation setting CVS1
Method | Datasets | |||
|---|---|---|---|---|
E | IC | GPCR | NR | |
MGRNNM [11] | 0.9955 (0.0003) | 0.9947 (0.0004) | 0.9785 (0.0020) | 0.9660 (0.0056) |
SMGRNNM [11] | 0.9798 (0.0004) | 0.9829 (0.0012) | 0.9531 (0.0028) | 0.9083 (0.0058) |
MC [78] | 0.9596 (0.0015) | 0.9415 (0.0015) | 0.8110 (0.0055) | 0.5882 (0.0253) |
MCG [79] | 0.8753 (0.0023) | 0.9539 (0.0010) | 0.8977 (0.0047) | 0.8315 (0.0165) |
WGRMF [20] | 0.9647 (0.0013) | 0.9747 (0.0022) | 0.9432 (0.0010) | 0.8892 (0.0153) |
WKNKN + L1,2-GRMF [77] | – | – | – | – |
RLS-WNN [25] | 0.9635 (0.0014) | 0.9786 (0.0026) | 0.9458 (0.0044) | 0.9329 (0.0114) |
CMF [35] | 0.9705 (0.0013) | 0.9832 (0.0008) | 0.9493 (0.0031) | 0.8679 (0.0124) |
NRLMF [36] | 0.987 (0.001) | 0.989 (0.001) | 0.969 (0.004) | 0.950 (0.011) |
TMF [28] | 0.989 (0.001) | 0.989 (0.001) | 0.9830 (0.003) | 0.978 (0.008) |
DDR [80] | 0.97 | 0.98 | 0.96 | 0.92 |
Proposed method | 0.9941 (0.0008) | 0.9958 (0.0005) | 0.9832 (0.0022) | 0.9698 (0.0062) |