Fig. 10

Simulation of the ODE system for the Edelstein network using different starting values of \(B_{tot}\) and [A]. The system converges to two equilibrium states; a “lower” one at \([A] \approx 1\) and a “higher” one at \([A] \approx 1.75\). If the system starts with a low concentration of A a switch between “low” and “high” equilibrium states happens at smaller concentration of \(B_{tot}\). Vice versa, if the system starts with a high concentration of A, the switch between the equilibrium states happens at higher concentrations of \(B_{tot}\)