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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism

Fig. 3

Exploration of impact of proportionality constant on predicted flux in glycerol carbon source in E.coli (Gerosa dataset): A growth, B acetate uptake/ = secretion, C glycerol uptake, D pyruvate dehydrogenase (PDH), E triose-phosphate isomerase (TPI), F ribose-5-phosphate isomerase (RPI), G ribulose 5-phosphate 3-epimerase (RPE). Data from growth simulations (A) are used to identify optimal values for the proportionality constant as those for which model predictions match experimental values. Simulations of internal and external flux were done by fixing the fitted values followed by sampling of the solution space. The error bars indicate the standard deviations

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BMC Bioinformatics

ISSN: 1471-2105

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