Fig. 1From: Aird: a computation-oriented mass spectrometry data format enables a higher compression ratio and less decoding timeA Traditional mzXML-like indexing, MS data is sorted by retention time. The retention time and spectrum start position are stored as an index. B In DDA, each MS1 spectrum is followed by 0-N MS2 data. Extracted ion chromatogram is generally calculated in successive MS1 data, so reordering MS1 data to put them in the same physical file block can speed up file reads. C Typically used in SWATH/DIA, every MS2 data belongs to a particular m/z SWATH window. MS2 data in the same window will be frequently accessed and calculated. Reordering is essential for fast file I/OBack to article page